Original Plant:Seed of Sophora japonica L.
Synonyms: CI 75610; Genestein; genisteol; genisterin; prunetol; sophoricol
Chemical Name:4',5,7-trihydroxyisoflavone 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Molecular Formula: C15H10O5
Molecular Weight:l 270.23
CAS No.: 529-59-9
Melting point: 297~298C
Solubility: Soluble in DMSO and Ethanol,hardly dissolve in water.
Pharmacology Action: Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities.