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5'-Deoxy-5-fluorouridine
5'-Deoxy-5-fluorouridine
Appearance:white crystalline powder
Soluble:soluble in water
Loss on drying:not more than 0.5%
Heavy metals:not more than 10ppm
Assay:99%
Use(purpose):anticancer
5'-Deoxy-5-fluorouridine (5'-dFUrd; Roche 21-9738) is a recently synthesized antineoplastic agent with therapeutic potential. The sensitivity of Ehrlich ascites tumor cells in CF-1 mice to 5'-dFUrd, as well as to 5-fluorouridine, was established. 5'-dFUrd was a more effective antitumor agent and was less toxic over a wide dosage range (50 to 400 mg/kg) than the other agents tested as measured by: the ability to prevent gross development of inoculated tumor; 45-day survival; and weight change over the treatment period Tags Anticancer 5 -Deoxy-5-fluorouridine
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