Cycloastragenol (1.00%-99.00%)


Plant source: The dry root of Astragalus membranaceus (Fisch.) Bge. (Main origin of Gansu) or Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao (Main origin of Inner Mongolia)
Appearance: Brown yellow powder (5%, 10%), Light yellow powder (50%, 90%), White powder (98%)
Molecular Formula: C30H50O5
Molecular Weight: 490.72
CAS No.: 78574-94-4, 84605-18-5
Assay Test method: HPLC-RID or HPLC-ELSD

Other Inspection item:

Loss on drying: ≤ 1.00-5.00%
Ash: ≤ 1.00-5.00%
Arsenic (MDL0.05): ≤ 1.5ppm
Lead (MDL0.02): ≤ 5.0ppm
Cadmium (MDL0.02): ≤ 0.3ppm
Mercury (MDL0.005): ≤ 0.1ppm
Total plate count: ≤ 1000cfu/g
Mould&Yeast: ≤ 100cfu/g
E.Coli: Negative
Salmonella: Negative

The Characteristic of Chengdu King-tiger Cycloastragenol:

1. Chengdu King-tiger Cycloastragenol product does not contain open-ring by-products astragenol, to ensure product safety and effectiveness (see "Customer Notice").
2. Cycloastrageonl 98% is pure white powder, HPLC purity is 99% above, can be directly used as a reference substance.
3. 100% natural extract of Astragalus: low purity of Cycloastragenol, in addition to contain Cycloastragenol, the other ingredients are all natural ingredients of Astragalus, such as Astragalus Polysaccharides, Astragalus Saponins, Astragalus flavone etc.
4. All specifications can be provided from stock in large quantity at any time. Third-party test report will be provided with Cycloastragenol.
5. KING-TIGER® Astragalus Extract Products Can Fully Meet the Requirements of EU Regulations on PAHs.

Customer Notice:

Different species of the plant Astragalus have been traditionally used in a wild variety of herbal blends and “natural” remedies in China and other regions in Asia for thousands of years. They contain Astragalosides (Including Astragaloside IV), which are the ultimate source of the purified Cycloastragenol.
Cycloastragenol production process involves different steps, which are not novel, e.g., not involving new types of heat processing or non-thermal preservation methods, new processes to chill or freeze products or to dehydrate products, the application of new processes catalyzed by enzymes, etc. All steps are well experienced in the food supplement industry.
We found that not thoroughly studied production process will generate a large amount of by-products named astragenol. Due to the similar structure with Cycloastragenol, it is hard to separate the two when using HPLC to determine the assay, resulting in higher measured value than the actual value.
After seven years of research, the production technology Chengdu King-tiger have developed can avoid producing astragenol, ensure the safety and effectiveness of the product. The detection method we used can completely separate astragenol and Cycloastragenol to ensure reliability of quality testing.
We take the Cycloastragenol 98% on the market and the Cycloastragenol 98% produced by us for example:
For the Cycloastragenol 98% on the market, according to the detection methods provided by suppliers, the chromatogram is as follows, COA reported value is 98.74%.

Chromatogram 1: Cycloastragenol 98% on the market and its testing chromatogram

But according to our detection methods, the testing result is only 60.45% in fact, HPLC chromatogram as follows. We can clearly see that there exists a large amount of astragenol.

Chromatogram 2: Cycloastragenol 98% on the market, tested by Chengdu King-tiger methods

For the Cycloastragenol 98% produced by Chengdu King-tiger, HPLC chromatogram as follows. There is completely no existence of astragenol and the purity reaches 99.33% for real.

Chromatogram 3: Cycloastragenol 98% produced by Chengdu King-tiger

NMR spectra also confirmed the purity of Cycloastragenol 98% produced by Chengdu King-tiger.

Chromatogram 4: 1H-NMR of Cycloastragenol 98% produced by Chengdu King-tiger

Report 5: Chengdu King-tiger Cycloastragenol 98% test report from USA authorized independent third party lab(Intertek)

Please carefully screened when you want to purchase Cycloastrageol and purchase from professional manufacturers to avoid purchasing inferior quality products.


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